Supported by IEEE organizations, Web of Science and many International academic institutions, three main objectives describe BioSMART 2019. The first one consists in communicating and promoting advanced researches in Bio-Engineering applications such as Biomedical engineering, Biometrics, Bionics, etc. The second objective consists in promoting multidisciplinary techniques, methodologies and approaches as well as collaborative projects involving more than one Bio-engineering topic. Finally, the third main objective is to highlight the applications aiming to connect Bio-engineering to Smart technologies (e.g. Smart clothes, wearable technologies, connected health, etc), from signal and image methodologies to smart consumer electronics. BioSMART will be the best and the perfect moment and the right place where researchers from different Bio-engineering fields can meet and exchange ideas to build outstanding and innovative future projects.